Gavin Ray @GavinRayDev

Work @PromptQL (@HasuraHQ) OSS Contributor. I have a Postgres tattoo 🐘🎨 🔬🧪🧬Passion for Molecular Bio, Health, Fitness, Longevity 💪Aspiring Bodybuilder github.com/GavinRay97 Seattle, WA Joined June 2018

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Gavin Ray @GavinRayDev

2 hours ago

@Dragotto Daily 20-30m incline treadmill and BP medications (Telmisartan + Nebivolol) are mandatory if you want to blast massive amounts of gear without dying...

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Gavin Ray @GavinRayDev

2 days ago

@NocturnalNelly What a transformation! Great insertions and proportions

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Gavin Ray @GavinRayDev

2 days ago

@DeanTTraining The data don't support frequency as a modulator of hypertrophy independent of volume: pubmed.ncbi.nlm.nih.gov/41343037/ Frequency is useful insomuch as it allows for more total volume, or for distributing sets over multiple days to ensure quality/intensity stay high.

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Gavin Ray @GavinRayDev

2 days ago

@SeeFisch Hats off to all the people who died of vulnerable plaque rupture with a CAC score of ~=0, because CAC can't detect non-calcified plaque... 💀 Sense of false safety, IMO

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Gavin Ray @GavinRayDev

2 days ago

@SeeFisch Arguably everyone should be on a statin and GLP-1 as preventative measures. Assuming no side effects/drugs are well-tolerated. The systemic health benefits and reduction in disease/mortality risk are immense. Same argument for low-dose PDE5 inhibitors x.com/scottisaacsmd/…

Scott Isaacs @scottisaacsmd

3 days ago

GLP1 RAs reduce inflammation in multiple disease models by affecting IL1β, IL6, TNFα, ands the NLRP3 inflammasome. These actions help explain benefits beyond glucose control and weight loss. academic.oup.com/jcem/article-a…

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Gavin Ray @GavinRayDev

2 days ago

@PGC1a_RB They beat my high score 😢

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Gavin Ray @GavinRayDev

2 days ago

@DrKERMD @PaleoOnc I hate medical clearance because it belittles the patient and takes agency/personal choice away from them. It should be up to an individual to decide what an acceptable amount of risk is. Of course the provider can decline, but still. Post-MI everyone wants cardio clearance...

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Gavin Ray @GavinRayDev

2 days ago

@DeanTTraining > You do NOT need to run AT ALL to look great and be extremely healthy 100%, though we know that lifting and cardio have complementary health benefits and metabolic changes Especially if you're concerned with cardiovascular health Unfortunately, cardio feels awful 🤣

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Gavin Ray @GavinRayDev

2 days ago

@BBSchizo777 Never noticed how bad Nick's clavicle genetics are You can see the others have almost ideal horizontal clavicles, but Nick has diagonals that work against producing a wide look Just goes to show that some subpar insertions/bone structure doesn't stop you from being elite

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Gavin Ray @GavinRayDev

2 days ago

100%, everyone at the competitive level is doing roughly the same thing in terms of PED's, and jabbing yourself is the easy part It's the diet, maintaining intensity in training, and (biggest factor IMO) not getting injured that's hard!! PED's are like multivitamins in my $0.02: you take them and then forget about them because that's not the hard bit

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Gavin Ray @GavinRayDev

2 days ago

I'm not sure why there's such a big debate about PED's online I've been BB'ing for +15 years, with a few friends + acquaintances at the pro level. Whenever I ask about drugs, I get roughly the same answer from all of them: Mass phase is: - Test as high as tolerated (anywhere from 1.5g - 3.0g) - EQ/Primo low-dose to control E2, no AI usage (typically 150-300mg EQ, or 200-400mg Primo) - 10iu GH (some guys push up to 20iu or more) - 5-10iu Huma/Nova pre-workout (some guys use another 5-10iu post-workout) - Basal insulin like Lantus/Tresiba if calories + carbs are insanely high (+5,000-7,000kcal) - 100-200mcg IGF1-LR3 post-workout, or pharma Increlex IGF-1 if they can get it Contest prep is: - 350-700mg Test - 200-500mg Tren - 4-10iu GH - 400-600mg Mast AND/OR 400-800mg Primo - Last 6-8 weeks: 50mg Anavar AND/OR 50mg Winstrol - Last 1-2 weeks: Halo or Sdrol I hope nobody pays hundreds of dollars for this info, lol...

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Gavin Ray @GavinRayDev

2 days ago

> "Worse yet, emerging research suggests GLP drugs may directly affect the cells that maintain collagen and skin structure" I've not heard this before. Looking into it, the claim seems to originate/be present in this one study: "GLP-1RA and the possible skin aging" link.springer.com/article/10.100…

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Gavin Ray @GavinRayDev

2 days ago

@joeljackson > If they take BPC and heal fast, we hear the story: "Oh my god, BPC worked." The "incidental effect": Someone happens to be taking some supplement, and an outcome occurs -- but it's impossible to tell whether it would have happened anyways So many anecdotes like this...

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Gavin Ray @GavinRayDev

2 days ago

People have no shame =/ Using LLM's to generate text meant to be read by humans is an asymmetry-of-investment problem: The author invested no time, but expects readers to invest time That's deeply disrespectful. LLM text should be treated like a compiler: Only machine-readable output

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Gavin Ray @GavinRayDev

2 days ago

@drmikehart @theproof > You can get equal LDL/apoB reduction with Ezetimibe + Statin + Bempedoic Acid For sure, though I've seen a few papers looking at PCSK9 inhibitors as add-on therapy to Statin + Ezetimibe and the results were solid Can lower LDL even further! pmc.ncbi.nlm.nih.gov/articles/PMC12…

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Gavin Ray @GavinRayDev

2 days ago

As someone on DAPT (Ticagrelor + 81mg Aspirin) post-MI for a year, and Aspirin for life, some thoughts: - Ticagrelor's antiplatelet effects are so much stronger, bleeding duration from minor things was massively increased - Aspirin has anti-inflammatory and pleitropic effects [0] [1] I'd consider Aspirin so relatively mild compared to P2Y12 inhibitors, with additional health benefits. I am not a doctor though, just a layman with an interest in pharmacology and personal experience with these medications. What're your thoughts on the above? [0] pmc.ncbi.nlm.nih.gov/articles/PMC11… [1] pubmed.ncbi.nlm.nih.gov/31669590/

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Gavin Ray @GavinRayDev

2 days ago

@GaintrustMikey That downlighting makes your triceps look insane, hell yeah

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Gavin Ray @GavinRayDev

2 days ago

@nick_krontiris This is the main reason why I wear a fitness watch. Since AI is getting so advanced, I assume that the historical data it's capturing will eventually be usable for predictive health analysis and preventative measures Better to start recording data for AI analysis now

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Gavin Ray @GavinRayDev

2 days ago

@drmikehart So jealous, I would kill for this. Something is wrong with my CNS. Seems like I'm stuck in persistent autonomic arousal -- I get near-zero minutes of Deep Sleep a night, sometimes less than 60m REM. RHR of 90-100, HRV is sub 10-ms (never seen such a bad HRV, kinda concerning)

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Gavin Ray @GavinRayDev

2 days ago

@julianhyde What a brilliant idea in hindsight! Add a boolean execution operator that uses some fast (likely on-device) LLM to evaluate a row Now the problem is "convince devs not to write every SQL query as one giant natural language statement" 🤣