Aakash Saraiya @EMedVC

@Averywalker21 @ThroneScience And to your point, if the polyp is still small/early might not have heme in stool consistently. But with continuous monitoring, maybe able to detect over a period of weeks/months.

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Aakash Saraiya @EMedVC

2 months ago

True for specificity but for population scale, detecting heme fragments/blood in stool is probably the best initial test. With a + test, can escalate to invasive procedures or further stool analysis for methylated dna fragments. Akin to the Apple Watch for arrhythmia detection - gets you in the door/begins the care journey.

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Aakash Saraiya @EMedVC

2 months ago

@Averywalker21 @ThroneScience Stool! False positive for hemorrhoids/fissures, but at scale can likely be very sensitive test. Much cheaper than a pan-scope approach.

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Aakash Saraiya @EMedVC

2 months ago

As a physician who has witnessed the uptick of young adults coming through the ER with abdominal complaints who subsequently get diagnosed with colon cancer, I was beyond excited when I first met @ScottHickle and he told me about his long term vision for Throne. Pumped for the @ThroneScience team on their Series A! Kick the shit out of colon cancer.

Scott Hickle - Poop Guy @ScottHickle

2 months ago

I'm thrilled to share that @ThroneScience has raised $10M to advance our vision of building a smoke detector for colon cancer. We started this company three years ago, and in that short period of time we built a world-class health tracker that our members often compare to

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Aakash Saraiya @EMedVC

2 months ago

@ScottHickle @ThroneScience Ye said it best “you are now watching the Throne, don’t let me get in my zone” Let’s go!!!!

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Aakash Saraiya @EMedVC

3 months ago

@ScottHickle @ThroneScience Scott you are a gem of a person, extremely proud investor and user!

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Aakash Saraiya @EMedVC

3 months ago

@ClearThinker66 @CanesDavid Agree on the imaging, labs I would argue otherwise. Triage nurses are actually very very good at what they do. Can usually determine accurately which patients should have labs cooking.

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Aakash Saraiya @EMedVC

3 months ago

@jaschmd @CanesDavid agreed, def not ideal, but extremely common place. Gives the illusion of care moving forward, and to be fair, many of those labs would be ordered anyway. Imaging should not be. But commonly is.

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Aakash Saraiya @EMedVC

3 months ago

David, the level of condescension is abhorrent. I did a urology rotation, does that make me a urologist? My job is not to make a home run diagnosis, it’s to rule out the shit that can be disastrous if missed. We make med students and residents do ER rotations so they appreciate the need to keep a broad differential, not oh I’ve seen this 15 times so let me try to pattern match. Sounds like you may need to repeat one, if the approach you take to a septic post op patient is a kub? Yes you are right, I can read a note, but can I tell you how often notes aren’t completed or done at a different facility? I didn’t say I’m getting a ct on every patient that walks into the ER, I said in the patient you described I have and I would. Surgeons botch shit all the time.

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Aakash Saraiya @EMedVC

3 months ago

Brother, this is a hyper specific and a great example of “you have all the information”. This is an undifferentiated septic patient, until proven otherwise. So unless I get a call from the urologist who is sending this person in or I see an Op note, I am ordering a CT 12/10 times. No inpatient team will admit this, just because the stent is properly placed. Unless you are the admitting and want to take the liability. I would encourage every specialist who thinks similarly to come work a shift in the ER, if I could have patient who can articulate what procedure they had done, have a urologist who would pick up my call at 11pm while also maintaining a door to dispo time sub 4 hours, and an admitting service that would accept this, I would pay you any amount of money. Also let’s not forget the other 20 patients I have with similar vitals and history and the waiting room full of patients. A CT, hate it or love it, allows me to gauge stability - does this person need the OR, ABx, stat consult, IR, etc.

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Aakash Saraiya @EMedVC

3 months ago

@YultideH My friend this is every healthcare startup company ever. Lots of promises and very little data…yet

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Aakash Saraiya @EMedVC

3 months ago

As a doctor who uses ultrasound daily, seeing other doctors overreact to a generation 1 product from a startup is hilarious. Abundant imaging is and should be the only future. MidJourney may or may not be it, but it’s directionally correct.