RNA-Seq Blog @RNASeqBlog
Transcriptome Sequencing Research & Industry News rna-seqblog.com Joined June 2014-
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An @NIH grant will support research on how cells identify defective RNA, with RNA sequencing helping students and researchers investigate nonsense-mediated decay and UPF1-driven RNA quality control. - @clasvillanova - @VillanovaU rna-seqblog.com/villanova-biol…
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Spatial RNA sequencing combined with Raman microscopy identified molecular signatures of senescent cells, offering a more detailed view of how aging changes tissues and gene activity. - @MIT @MassGenBrigham @harvardmed @broadinstitute @ragoninstitute rna-seqblog.com/unmasking-zomb…
RNA sequencing can detect fusions, splice events, and transcript isoforms that DNA testing may miss, while RNA variant imaging shows where those changes occur within tumor tissue. - @Harvard rna-seqblog.com/rna-variant-im…
Single-cell RNA sequencing distinguished newly made RNA from maternal RNA, revealing how MTA retrotransposons help regulate zygotic genome activation and early embryonic development. - @Tongji_Uni rna-seqblog.com/single-cell-ti…
rna-seqblog.com/a-real-data-ap… sequencing can uncover transcript-level changes missed by gene-level analysis, and a new real-data framework compares DTU methods across bulk, single-cell, spatial, long-read, and short-read datasets.
RNA sequencing revealed two shared molecular patterns across genetically diverse autism-risk mouse models, with differences influenced by sex, development, brain region, and drug exposure. - @IBS_media rna-seqblog.com/autism-risk-mu…
Single-cell RNA sequencing reveals gene activity in individual Aedes aegypti midgut cells, helping researchers identify cell populations and understand how mosquito tissues respond to pathogens. - @YaleMed - @Yale rna-seqblog.com/single-cell-rn…
RNA sequencing identified human RNAs carrying newly characterized Ap2N caps, revealing new tRNA-derived fragments and providing insight into RNA processing, modification, and stress responses. - @CzechAcademy rna-seqblog.com/detection-and-…
RNA sequencing reveals complex patterns across individual cells and tissues. New AI models may help researchers interpret single-cell RNA sequencing and spatial transcriptomics data across multiple biological scales. - @cardiffuni rna-seqblog.com/new-ai-approac…
RNA sequencing helped identify mRNAs prone to aggregation, revealing sequence features that may influence RNA solubility and inform the design of mRNA therapeutics. - @WhiteheadInst - @MIT rna-seqblog.com/messenger-rna-…
RNA sequencing read length can affect A-to-I editing measurements. Long-read RNA sequencing may improve accuracy by mapping edited reads more reliably to the genome. rna-seqblog.com/short-read-rna…
RNA sequencing can reveal more than RNA abundance. qMAP analyzes RNA fragmentation patterns that may uncover regulatory changes linked to development, disease, reproduction, and aging. - @unevadareno - @unrmed rna-seqblog.com/qmap-reveals-r…
hRNA sequencing helped identify the newly discovered Asian longhorned tick nairovirus, highlighting its value for detecting emerging pathogens and distinguishing infections with similar symptoms. - @CAS__Science rna-seqblog.com/rna-sequencing…
RNA sequencing accuracy for alternative splicing depends heavily on data quality, sequencing depth, and bioinformatics choices. Large-scale benchmarking helps define more reliable workflows for splice and isoform analysis. rna-seqblog.com/benchmarking-r…
Small RNA sequencing revealed distinct snoRNA-derived RNA patterns in healthy blood cells and AML, linking these small RNAs to gene regulation, leukemia biology, and patient outcomes. - @uniklinik_hd rna-seqblog.com/small-rna-sequ…
Single-cell RNA sequencing links cancer mutations with cell states and gene expression, helping researchers trace clonal evolution, identify resistant populations, and uncover potential therapeutic vulnerabilities. - @IcahnMountSinai - @WeillCornell rna-seqblog.com/single-cell-rn…
Single-cell RNA sequencing of more than 87,000 cells revealed extensive cellular reprogramming during acorn worm metamorphosis, showing how larval cells can adopt new adult identities. - @Stanford - @HopkinsMarine rna-seqblog.com/worms-radical-…
POND-seq enables repeated RNA sequencing from living cells, allowing researchers to track gene expression and RNA-protein interactions over time without destroying the cells. - @PKU1898 rna-seqblog.com/pond-seq-enabl…
RNA sequencing can measure gene activity in individual cells and entire early embryos, helping researchers track how cells specialize and developmental programs emerge. - @univ_paris_cite - @CarnotOpale - @Inserm rna-seqblog.com/single-cell-an…
A new live-cell RNA sequencing approach uses virus-like particles to release RNA without destroying cells, allowing researchers to track gene expression changes in the same cell population over time. - @broadinstitute - @MIT rna-seqblog.com/new-method-all…
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