The Intern At Work @InternAtWork
Your Canadian internal medicine podcast written by residents for residents and students. By @AlisonLaiMD, @KallirroiLaiya, & @MeraliZahra. linktr.ee/internatwork Hamilton, Ontario Joined May 2018-
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📚 New Cardio Trial Files! ❤️ Mavacamten reduced LVOT gradients in adolescent HOCM 💊 Enlicitide lowered LDL-C by 64.6%, outperforming other oral nonstatins ⚖️ Weight loss did not improve AFib symptoms in LOSE-AF 🔗 cardiotrialfiles.substack.com/p/cardio-trial… #Cardiology #MedTwitter
📬 Stay in the Loop with Medicine Pods! Sign up for our monthly newsletter at medicinepods.com to get the latest podcast episodes and medical infographics, delivered straight to your inbox! #MedEd #MedTwitter
📚 New IBD Trial Files! 🏠 Proactive home fecal calprotectin monitoring did not prevent UC flares 💉 Anti-TNF withdrawal led to more flares than continued therapy (52% vs. 12%) 🔗 ibdtrialfiles.substack.com/p/ibd-trial-fi… #IBD #UlcerativeColitis #MedTwitter
📚 New Trial Files Throwback! 🫁 5 days of prednisone was enough for COPD exacerbations 💧 Balanced crystalloids reduced adverse kidney events vs saline 🫘 Canagliflozin improved renal outcomes in T2DM + CKD 🔗 trialfiles.substack.com/p/trial-files-… #MedTwitter #TrialFiles
📚 New AllergyImm Trial Files! 🎨 Upadacitinib ↑ repigmentation in vitiligo 💇 Deuruxolitinib ↑ hair regrowth in alopecia areata 🧴 Lebrikizumab was effective in atopic dermatitis regardless of atopic comorbidities 🔗 allergyimmtrialfiles.substack.com/p/allergy-and-… #Allergy #Immunology #MedTwitter
📚New Heme Onc Trial Files! 🧬Tafa-len-R-CHOP improved PFS in high-risk DLBCL 💊Pirtobrutinib outperformed ibrutinib in CLL/SLL 🎯Pola-R-GemOx improved survival in relapsed DLBCL 🔗hemeonctrialfiles.substack.com/p/heme-onc-tri… #HemeOnc #MedTwitter
📚New Thrombo Trial Files! 🫁YEARS safely ↓ CTPA use in cancer patients 💉Intermediate-dose heparin offered no benefit in critical COVID-19 🦵Aspirin alone was noninferior for VTE prevention after hip/knee arthroplasty 🔗thrombotrialfiles.substack.com/p/thrombo-tria… #Thrombosis #VTE #MedTwitter
🎙️ New The Intern at Work! 🫁 High Stakes, with Low Pressures: An Updated Guide to ARDS Brush up on ARDS with an updated, practical approach to diagnosis and management at the bedside. 🎧 Listen: medicinepods.com/the-intern-at-… #MedEd #ARDS #CriticalCare
📚 New Diabetes Trial Files! 💊 Oral orforglipron outperformed dapagliflozin for HbA1c reduction 💉 CagriSema improved HbA1c & weight without more hypoglycemia 📈 Retatrutide delivered impressive glycemic control as monotherapy 🔗 diabetestrialfiles.substack.com/p/diabetes-tri… #Diabetes #MedTwitter
📚New Critical Care Trial Files! 🩸Frozen platelets were not noninferior for surgical bleeding 🫁Post-op pneumonia markedly ↑ mortality after cardiac surgery 🫁Early extubation after thrombectomy offered no added benefit 🔗 criticalcaretrialfiles.substack.com/p/critical-car… #CriticalCare #MedTwitter
📚Cardio Trial Files Throwback ❤️Dapa ↑ cardiometabolic outcomes after MI but not CV death or HF hospitalization 🫀Edoxaban offered no net benefit for device-detected AHREs 🧬Lepodisiran ↓Lp(a) by up to 97% with a single dose 🔗cardiotrialfiles.substack.com/p/cardio-trial… #Cardiology #MedTwitter
📚New Trial Files! 🦠Cefazolin was noninferior to ASPs for MSSA with less AKI 💊Oral fosfomycin replaced IV β-lactams for selected complicated UTIs 🫁YEARS reduced CTPA use in cancer patients with suspected PE 🔗trialfiles.substack.com/p/trial-files-… #MedTwitter #FOAMed
🎙️ New Intern at Work episode! 🩸 When should you suspect porphyria? 🧪 A practical approach to diagnosis 💊 Acute management, triggers & key clinical pearls 🎧 medicinepods.com/the-intern-at-… #MedTwitter #FOAMed #InternalMedicine
📚New Heme Onc Trial Files Throwback! 🧬Ibrutinib improved frontline outcomes and questioned the role of ASCT 💊Acalabrutinib+R-CHOP showed outstanding response rates 👥Acalabrutinib+BR prolonged PFS in older patients with MCL 🔗hemeonctrialfiles.substack.com/p/heme-onc-tri… #HemeOnc #MedTwitter
🚨 New Intern at Work episode! ⚠️ An Approach to Anaphylaxis Learn how to: 💉 Recognize anaphylaxis 🩺 Use IM epinephrine appropriately 🏥 Manage observation and discharge ✍️ Educate patients before they leave 🎧 Listen: medicinepods.com/the-intern-at-… #FOAMed #MedEd #Anaphylaxis
📚Nephro Trial Files Throwback! 🩺Finerenone reduced CKD progression and CV events in T2DM 🩸STARRT-AKI found no benefit to accelerated dialysis initiation 💧High-dose hemodiafiltration reduced mortality vs conventional HD 🔗nephrotrialfiles.substack.com/p/nephro-trial… #Nephrology #MedTwitter
📚New Critical Care Trial Files Throwback! 🫁ACURASYS suggested benefit with early paralysis ⚖️Routine neuromuscular blockade = no mortality benefit 🔄Early prone positioning dramatically improves survival in severe ARDS 🔗criticalcaretrialfiles.substack.com/p/critical-car… #CriticalCare #MedTwitter
📚New Cardio Trial Files! 🫀LAA closure was noninferior to NOACs & ↓ bleeding in AF 🩺IVUS-guided PCI had no advantage over angiography for left main PCI ⚡Sodium bicarb didn't improve ROSC in in-hospital cardiac arrest 🔗cardiotrialfiles.substack.com/p/cardio-trial… #CardioTwitter #MedTwitter
📚New IBD Trial Files! ✂️Surgery vs infliximab for localized ileal Crohn's 📊LIR!C showed similar short-term outcomes, while the 10-year follow-up found significantly more patients remained therapy-free after surgery. 🔗ibdtrialfiles.substack.com/p/ibd-throwbac… #IBD #GITwitter #MedTwitter
📚New Trial Files! 🫀Sodium bicarb didn't improve ROSC in in-hospital cardiac arrest ⚖️Continuing tirzepatide maintained greater long-term weight loss ❤️Stopping β-blockers after MI with preserved EF was noninferior to continuing 🔗 trialfiles.substack.com/p/trial-files-… #MedTwitter #FOAMed
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