Sebastian Greiss @GreissLab
Genetic code expansion, optogenetic tools, behaviour in C. elegans at the University of Edinburgh Scotland Joined March 2020-
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Check out our new paper for site-specific labeling proteins and building defined Ub/Ubl-protein conjugates using a plant Asp-endopeptidase. Great effort by @MaxFottner @jhmgrtnr @MaxGantz_ @RaMue1304 and @NkTimon! Congratulations to all!👩🔬👨🔬🤩🙌🥳
Site-Specific Protein Labeling & Generation of Defined Ubiquitin-Protein Conjugates Using an Asparaginyl Endopeptidase @ETH_DCHAB @ETH_en @klanglab @TU_Muenchen @MaxFottner #SiteSpecific #ProteinLabelling #Ubiquitin #Conjugates #Asparaginyl #Endopeptidase pubs.acs.org/doi/10.1021/ja…
Generation of Photocaged Nanobodies for Intracellular Applications in an Animal Using Genetic Code Expansion and Computationally Guided Protein Engineering (Greiss) @GreissLab, @jack_oshea97 #openaccess onlinelibrary.wiley.com/doi/10.1002/cb…
1/7 Try our new app for optimizing transgenes for C. elegans expression (wormbuilder.org/transgenebuild…). The app uses algorithms from collaborators Henrik Bringmann (TU Dresden) and Dan Dickinson (UT Austin) - or codons from highly expressed ubiquitous genes.
1/5 Our paper is out as a bioRxiv preprint. @sonia_elmouridi and @FaisalMAlkhaldi Like MosSCI, just better. Targeted single-copy and array integration synthesizing new and gradual improvements from the past 15 years across many labs. biorxiv.org/content/early/…
Come and join us @Wallace_Lab @SBSatEd for your PhD in #biotechnology, investigating the use of #microbes to produce industrial chemicals from sustainable feedstocks and waste with @LubrizolCorp. Fully-funded studentship to start Oct '22 @SynthSysEd findaphd.com/phds/project/a…
Now in its final format and online as a hot paper 🔥😀 A great collaboration with the @SieberLab to profile the substrate scope of hClpP via genetic code expansion, photocrosslinking and proteomics! Congrats Anh, Thomas, Timon and everyone involved!! 🙌
Substrate Profiling of Mitochondrial Caseinolytic Protease P via a Site-Specific Photocrosslinking Approach (Lang) @SieberLab @klanglab #openaccess onlinelibrary.wiley.com/doi/10.1002/an…
The Funding Elves have been good to @Wallace_Lab in December 🎁 We'll be advertising for 5 PDRAs (1 with @JoSadler10) and 1 fully-funded PhD at the start of 2022. DM or email me with a cover letter and CV if you're interested in joining us @SBSatEd @SynthSysEd 🧫🧬🧪
Then we use the quadruplet to incorporate photocaged cysteine into a caspase for light induced ablation of C. elegans neurons.
We use photocaged lysine to express photocaged Cre recombinase for optical control of gene expression. Here the UAGA quadruplet works as efficiently as a UAG triplet.
Check out our Breakthrough Article in @NAR_Open where we use a quadruplet codon to expand the genetic code of an animal. @EdinburghUni @CDBSEdinburgh @SynthSysEd @ERC_Research #Celegans academic.oup.com/nar/advance-ar…
Interdisciplinary EASTBIO PhD project available on drug resistance and human fungal pathogens combining #Calbicans, #Celegans, and #Bioinformatics @Makrantoni_lab @r0bah0lic @EdinburghUni Only few days left to apply!! Deadline Dec 15. findaphd.com/phds/project/e…
PhD studies? Come join us! @EdinUni_MeetCIR @EdinUni_IRR. gramhansenlab.com/join-us/ 🔬🧫🧪🧬
Check out the early view of our new article in @angew_chem! A fantastic collaboration with the @SieberLab to profile the substrate scope of mitochondrial caseinolytic protease P via site-specific photocrosslinking 🧪💡🧫🧑🔬🧑💼 Congrats to Anh and Thomas! 🙌 onlinelibrary.wiley.com/doi/10.1002/an…
Excited to share this new preprint! We optimized a directed evolution strategy to engineer E. coli tyrosyl-tRNA synthetase for genetically encoding new unnatural amino acids in mammalian cells, including a nonhydrolyzable phosphotyrosine mimic biorxiv.org/content/10.110…
Interested in drug resistance and human fungal pathogens? Apply for our interdisciplinary EASTBIO PhD project to join us at @UoE_IM. Co-supervisors @Doitsidou_lab @r0bah0lic. Fully-funded, international applicants. Please RT! #Calbicans #Celegans findaphd.com/phds/project/e…
Playing Lego with ubiquitin: 🧱🧪🧬 Building complex Ub/Ubl chains using orthogonal sortases. Great work led by @MaxFottner 👏 with help from @mariaweyh and Dominic! Many thanks to Stefan and @Michael13120606 for the NMR-collaboration! 🥳🥂@ERC_Research nature.com/articles/s4146…
Check out our recent work with @lehorsfall on the use of microbial Pd nanoparticles and membrane-bound micelles for chemical synthesis. Microbes are amazing chemists! @SynthSysEd @SBSatEd @EdinburghChem pubs.rsc.org/en/content/art…
Our paper on improved genetic code expansion and using a laser to control gene expression in C.elegans is out. Congrats to lab members Lloyd Davis @aggelikigoutou @AilishTynan Kieran Baxter, Zhiyan Xi @jack_oshea97 @EdinburghUni @CDBSEdinburgh @SynthSysEd elifesciences.org/articles/67075
Keke Zhang @keke65019
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Sandhya Jaiswal, PhD @Sandhyajais23
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Lidia Ripoll Sánchez @Lidia_Ripoll_S
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Dmytro Kukhtar @dkukhtk
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Zhenjie @ZhenjieLow
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Hamid Biochemist @HamidBiochemist
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Prof. Roger Pocock �... @RogerPocockMelb
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Maximilian Gantz @MaxGantz_
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Christian Froekjaer J... @wormbuilder
594 Followers 74 Following Assistant Professor @ KAUST. C. elegans genetic engineering and Synthetic Bio. Role of non-coding DNA in reducing epigenetic and transgenerational silencing.
Delia @Delia818GD
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Rick Escamilla @rick777pp
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Wojciech Pokrzywa @wojtek_pokrzywa
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Carolina Soares @C_FonsecaSoares
377 Followers 2K Following Neuroscience PhD candidate @kingscollegelon 🧠Science & Philosophy enthusiast 🇵🇹 Podcast co-founder @Neuroverse_pod 🦋 @carolina-soares.bsky.social
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Michael Francis Lab @FrancisLab4
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Shah Lab @ShahLabUCLA
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BANIBRATA MAITI @banibrata_maiti
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MOHAMED ALI ALI @MOHAMED57774453
568 Followers 5K Following Assistant lecturer in the chemistry department, faculty of science, Zagazig University-Egypt. Research in university of Chinese Academy of Science
High School CRISPR Ac... @utfriglowworms
431 Followers 234 Following High school research group led by Dr. Ryan Doonan, using C. elegans and CRISPR to accelerate scientific discovery and innovate high school S.T.E.M.
imm @immlml
21 Followers 389 Following
ZJU-UoE Institute @zje_institute
320 Followers 86 Following The Zhejiang University - University of Edinburgh (ZJE) Institute provides innovative teaching in Biomedical Sciences all from our new campus in China!
Manuela Hospenthal @M_Hospenthal
565 Followers 307 Following Molecular & Structural Biologist. Assistant professor at the Institute of Molecular Biology and Biophysics @ETH. Views are my own.
Julius Fredens @JuliusFredens
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Stella hellbergh @stella_jane21
4 Followers 228 Following I’m Stella of Britney panda lover🐼🖤🤍 Stella Jane aspiring 🚫fur coats I drink the Berber liquid
Haimantika Seel @HaimantikaSeel
146 Followers 3K Following PhD Student at Ben Gurion university, Israel @bengurionu
Humbeline Paupelin (V... @HumbelinePV
136 Followers 600 Following Scientist - working on synthetic biology & natural products - PhD from @GenoUMR_GM @UnivParisSaclay
CHEMISTRY WIDE @ChemistryWide
845 Followers 5K Following CHEMISTRYWIDE FOCUSING ONLY CHEMISTRY TOPICS
Aniruddha Das @_AniruddhaD
202 Followers 889 Following Postdoctoral Fellow at @shen_utah Lab Graduated from @wojtek_pokrzywa lab | Interested in Proteostasis and Ubiquitin-Proteasome system
Mick lab @MickLab
572 Followers 667 Following Using biochemistry, cell biology, proteomics and imaging techniques to unravel the molecular functions of mammalian primary #cilia. @mick-lab.bsky.social
Laura Molina-Garcia @LMolina_Garcia
219 Followers 225 Following PI at CNB-CSIC. Atraccion de Talento Fellow. Host-microbiome interactions. C. elegans Neural circuits. Bacterial amyloids.
Chris Wan @ChrisJWan
138 Followers 741 Following Synbio, origins of life. Postdoc @TheCrick Previously PhD student @MRC_LMB, undergraduate @CamBiochem
Arbely Lab @ArbelyLab
259 Followers 195 Following Biochemistry and synthetic biology lab at Ben-Gurion University of the Negev.
Dongchen Du @DongchenD
258 Followers 840 Following PhD student with @NadjaSimeth at @uniGoettingen & @MBExC_de. Alumna Heinis lab at @EPFL and Sun Yat-sen Uni.
Institut Jacques Mono... @IJMonod
3K Followers 1K Following Unité de recherche @CNRSbiologie @univ_paris_cite Recherche fondamentale en #biologie - Leading center for fundamental interdisciplinary research in #biology
Anja Bremm @AnjaBremm
504 Followers 340 Following Group leader @IBC2_GU, research focus on ubiquitin signaling & autophagy; peroxisome homeostasis
UK Prime Minister @10DowningStreet
5.6M Followers 194 Following Official page for Prime Minister @andyburnham's office, based at 10 Downing Street.
🏴�... @TartanArmyGroup
49K Followers 8K Following The X arm of the Tartan Army Group on Facebook. Administered by match going Scotland fans. 18+ No Scotland, No Party.
Sternberg Lab @SternbergLab
2K Followers 23 Following News from the Sternberg lab at Columbia Univ., HHMI. Posts are from lab members and not Samuel Sternberg unless signed SHS. Posts represent personal views only.
Drug Monkey @drugmonkeyblog
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Edinburgh Reproducibi... @Edinburgh_Tea
637 Followers 772 Following ReproducibiliTea sessions @EdinburghUni to discuss and learn more about reproducible and #OpenResearch while enjoying a cuppa ☕ @Edinburgh_open
Guy Poppy CB FMedSci @GuyPoppy1
2K Followers 1K Following Husband, Dad, Cyclist, Pro Vice Chancellor R&I UniBristol. Personal views. Former Chief Scientific Adviser (UK Govt). former Deputy EC and Exec Chair BBSRC
Ribosome Papers @ribosome_papers
3K Followers 1 Following New #Ribosome papers from #Pubmed, #bioRxiv, and #arXiv. Also blogged at: https://t.co/M6psKeTonp | maintained by @slavovLab and @slavov_n
Department for Scienc... @SciTechgovuk
214K Followers 3K Following As of 20 July, @scitechgovuk's responsibilities have transferred to @biztradegovuk, @DCMS and @cabinetofficeuk. Please follow them for updates.
Maria Leptin @mleptin
5K Followers 6 Following Passionate about fundamental research and human curiosity and creativity in all areas, my lab, EMBO (past director), ERC (current president). But family wins.
Elisabeth Bik @MicrobiomDigest
144K Followers 44K Following Science integrity consultant, PhD. #ImageForensics @METRICStanford affiliate / https://t.co/2xH3WdXTFr / https://t.co/V4MR7WV9tl 🇳🇱🇺🇸
Thomas Williams @Dr_Tom_Williams
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Surojit Sural @surojitsural
938 Followers 960 Following Interested in molecular plasticity of both first and second brains. Faculty member at @TIFR_Bio @TIFRScience
Prof. Roger Pocock �... @RogerPocockMelb
1K Followers 847 Following Worm geek. Spends most of his time understanding how genes control brain function. Monash University.
UK Science & Innovati... @UKSINet
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204K Followers 2K Following Supporting research to transform life, health and wellbeing. We’re taking on three urgent health challenges: mental health, climate change & infectious disease.
Engineering and Physi... @EPSRC
47K Followers 1K Following UKRI EPSRC is the UK's main funding agency for engineering and physical sciences research, part of @UKRI_News. Blog: https://t.co/jnvI69bpwL…
UK Research and Innov... @UKRI_News
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572 Followers 667 Following Using biochemistry, cell biology, proteomics and imaging techniques to unravel the molecular functions of mammalian primary #cilia. @mick-lab.bsky.social
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Javier Santoyo @jsantoyo
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246 Followers 210 Following Worm electrophysiologist. Assistant Professor in Neuroscience @CityUHongKong
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Ailish Tynan @AilishTynan
110 Followers 180 Following EASTBIO PhD student at the University of Edinburgh @EdinUni_IGC researching healthy ageing and dementia 👩🏼🔬🧬 Podcast addict and embroiderer 🧵 She/her 🌻
angel @aggelikigoutou
18 Followers 46 Following A Chemical Engineer with a Masters in Systems & Synthetic Biology and science enthousiast
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6K Followers 1K Following chemical/synthetic biologist, Luddite trying find better ways to make molecules that do important stuff, dad, @uchicago professor of chemistry
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80K Followers 69 Following Professor at Harvard and the Broad Institute. Our lab integrates chemistry & evolution to illuminate biology & enable new therapeutics. IG/Threads: @davidrliu1
Alanna Schepartz @AlannaSchepartz
4K Followers 2K Following Professor Chem/MCB, UC Berkeley. Director, Center for Genetically Encoded Materials (@cgem_cci). Editor-in-Chief @BiochemistryACS. Investigator, @czbiohub!
The Hackenberger Grou... @PhosphorusFive
2K Followers 348 Following We are a Berlin-based #chemicalbiology group thrilled about modifying proteins to advance biological research and drug development.Also known as the Hackenbees!
Dirk H. Trauner @DirkTrauner
16K Followers 12K Following Penn Integrates Knowledge Professor, Natural Product Aficionado, Photopharmacologist, Fox Terrierist, and Unfulfilled Architect. #firstgen
Leonardo Rios @DrLeoRios
9K Followers 8K Following Assoc Prof @UCLBiochemEng1 | #SynBio Metabolic Engineering Bioprocessing Scale up | Championing Microbial Cell Factories | Lead @LeoRiosLab |












