fleemanlab.bsky.social @FleemanLab
Assistant Professor at the University of Central Florida College of Medicine studying drug resistant Klebsiella pneumoniae. rfleeman97.wixsite.com/my-site Joined July 2016-
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Beyond excited that our manuscript on bac7(1-35) disruption of K. pneumoniae biofilms has been published in @PLOS pathogens! journals.plos.org/plospathogens/…
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@DavidAaronRosen Congratulations Shantal!!!
@TaniaWong88 Congratulations 🎉
fleemanlab.bsky.social retweeted
Our review on disulfide formation is out! Since the discovery the DSB system ~35 years ago, we have made great steps in understanding its role in processes like virulence and #AMR. In loving memory of my supervisor Stuart Ferguson. @nikikaderabkova Link: sciencedirect.com/science/articl…
@HaiderSManzer Congratulations Haider! Great to see you killin it!!
So excited to be in Vienna for #ESCMID2025 where I will be giving a talk on how our peptides can disrupt K. pneumoniae biofilms. If you are around this Tuesday come check it out!!!
Great weekend at #FLASM2025! I was so pleased to see my students work was well received! They were so excited to present their work!
fleemanlab.bsky.social retweeted
Our study appearing in @NatureComms showing the importance of the T6SS of Klebsiella pneumoniae in gut colonization. We combined tn-seq with metagenomics and identified new microbiota targets and T6SS regulators. nature.com/articles/s4146…
fleemanlab.bsky.social retweeted
I'm excited to announce our latest publication! We teamed up with @KHullahalli to barcode Klebsiella and ask basic questions about bacteremia pathogenesis: 1) how are bacteria shared between sites and 2) which host and bacterial factors influence dynamics? nature.com/articles/s4146…
Bacterial warfare is always so amazing!
OUT NOW - Streptomyces secretes a siderophore that sensitizes competitor bacteria to phage infection nature.com/articles/s4156…
It’s that time again! If you are interested in Klebsiella pneumoniae this is the seminar series to attend! So excited to see what this year will bring!!
It's that time of year! Registration and abstract submission for the 6th Klebsiella Seminar Series is now open. Participation is free and abstracts are due by February 16th. See the link below for details: forms.gle/gxbvaC6FjzuSPt… #KlebClub
@parasite_doc @Nature_NPJ @EpiDemiLogos @OlayaRendueles Thank you Dennis 😊
Check out our latest publication aligning the MRSN panel biofilm and mucoid phenotypes to the genotypes in @Nature_NPJ Biofilms and Microbiomes! Special thanks to my collaborators on this work @EpiDemiLogos and @OlayaRendueles !! nature.com/articles/s4152…
fleemanlab.bsky.social retweeted
Interested in a meaningful postdoc evaluating vaccine efficacy in a variety of murine models? Consider applying to join us @WUSTL @WashUMedPedsID @KlebClub wustl.wd1.myworkdayjobs.com/en-US/External…
Check out the most recent advances by the de la Fuente group using AI to change the face of antimicrobial discovery!
Antibiotic discovery is notoriously hard and slow. What if we could change that by optimizing antibiotics on the computer? Introducing APEXgo, our latest AI model, which integrates a transformer-based variational autoencoder with Bayesian optimization to design novel
fleemanlab.bsky.social retweeted
Our latest publication is out! journals.asm.org/doi/10.1128/jb… Lots of hard work from @AlexaGannon here, and the best bit is we get to celebrate at her PhD graduation this Friday 🥳 If you like Pseudomonas and aggregate biofilms take a look! #pseudomonas #aggregates #CF #proudPI
fleemanlab.bsky.social retweeted
🚨We have a "Scientist" position in my lab at @StJude 👉This position is stable and not dependent on external funding. 🗒️Ideally, the candidate holds a PhD in Microbiology or related and +3 years exp. post PhD. See details in ad. Please kindly retweet! talent.stjude.org/careers/jobs/J…
fleemanlab.bsky.social retweeted
Not long ago, discovering antibiotics meant painstakingly purifying compounds from sources like soil—a process longer than earning a PhD, often with limited success. Years ago, we envisioned that by treating biology as an information source and mining it with advanced algorithms, we could revolutionize antibiotic discovery. In my @PLOSBiology article, I summarize our progress over the past 5+ years. Today, my lab can discover hundreds of thousands of new antibiotic molecules in just a few hours—on a computer.
The rise of #AntibioticResistance calls for innovative solutions; @delafuentelab outlines how biology can be mined digitally using #ArtificialIntelligence as a new paradigm for antibiotic discovery, offering hope in the fight against superbugs #PLOSBiology plos.io/3B3rWP8
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