Emily K. Sims @EmKSims
Physician scientist at Indiana University Indianapolis, IN Joined June 2018-
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As always, such a pleasure to work with Erin Templeman from the @UniofExeter team, @RAOram, and Lauric Ferrat, as well as an excellent team of collaborators like @cevansmo @catespeake and others who are not on this platform. @IUSweetTweets
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3. Risk scores like HbA1c and metabolic indices performed better in adults 4. Unique patterns suggest a need for age-tailored screening and follow-up
2. Unlike those were were single Ab positive or met stage 1 T1D criteria, adults with stage 2 T1D at screening progressed at the same rate as children (78% in 5 years)
We found important differences exist in screening and progression amongst children and adults. For example: 1. Adults were more likely to screen single Ab positive compared to kids
Super excited this paper on islet autoantibody positive adults is finally online- we analyzed screening and #T1D progression in 100K adult relatives screened as part of @T1D_TrialNet . Available at: bit.ly/4md4scn
Really excited to share this super translational project from rockstar @chaipoorva ! Islets and T cells and EVs- what more could you want ❤️?
Beta cell extracellular vesicles carry PD-L1 and suppress CD8+ T cells. EV PD-L1 is increased in AAB+ individuals, correlating with residual beta cell function. Potential #biomarker for #T1D heterogeneity. #Diabetes @IUSweetTweets @emksims @chaipoorva tinyurl.com/4pe2hbvb
Should be a good one!
Join @TeresaMastracci , @claus_jorgensen , Maureen Gannon, and me at the Gordon Research Conference (GRC) on Pancreatic Diseases in June - "where the endocrine and exocrine pancreas meet". Registration is now open grc.org/pancreatic-dis…
Excited to work with this awesome team!
Thrilled to share our study: Risk associated with single autoantibody shifts after age 10, with men at higher T1D risk. Thanks to @EmKsims, @RAOram, @FerratLauric, and @T1D_TrialNet for their support. Read full press release here: shorturl.at/QojjQ #T1D #DiabetesResearch
Emily K. Sims retweeted
👋Meet us in #Indianapolis for our Complimentary CE Dinner Meeting on #Type1Diabetes on Monday, June 17th! ➡️ ow.ly/qakt50SelC2 @EmKSims #Diabetes #ContinuingEducation #HealthcareProfessionals #Continuingprofessionaleducation #FOAMed #endocrinology
@IUSweetTweets @WIELDvoice @IUMedSchool @EliLillyandCo @DoctorDiMeglio @cevansmo So thankful to have had the chance to learn from both of these superstars 😍😍😍
Emily K. Sims retweeted
Congrats to the global experts recognized as 2024 @WIELDvoice Trailblazers, especially @IUMedSchool Drs. Evans-Molina & DiMeglio and @EliLillyandCo Dr. Gimeno. We're proud and fortunate to have many female leaders in diabetes making an impact in Indiana! womenleadingdiabetes.com/diabetes-trail…
Great work by @JacobsenLM and @Heba_T1D supporting the idea that metabolic endpoints can give us a quick readout of T1D disease modification. And we know based on @DrPeteTaylor and Colin Dayan's data that these changes have clinical relevance for our patients with T1D!
@T1D_TrialNet identifies earlier trial end points that demonstrate a beneficial treatment effect at 6 months and predict benefit out to 12 months. This could allow for shorter early phase trials or adaptive designs. @ADA_Pubs Read Here➡️doi.org/10.2337/dc24-0…
@IUSweetTweets @IUMedSchool @JDRF @DoctorDiMeglio Super excited to have these two rockstars in our group @IUSweetTweets @DoctorDiMeglio !
Super excited for one of the best meetings of the year!
Registration is now open to attend the 20th Immunology of Diabetes Society Congress in Bruges, Belgium on Nov 4-8, 2024! Learn more about this year's program, register and submit an abstract by visiting idsbruges2024.com. #T1DResearch #DiabetesResearch #IDS2024
@BesserBesser Super exciting! #thefutureisnow
Do metabolic measures perform similarly for predicting T1D vs. assessing immunotherapy? Not necessarily. However, combined glucose and C-peptide measures were consistent performers for both purposes. Check out at bit.ly/482qeIc ! @T1D_TrialNet @IUSweetTweets
Emily K. Sims retweeted
Attending #nPOD2024! Come to our @WIELDvoice breakfast panel where we discuss opportunities & barriers to leadership.
Attending nPOD (npod.org/agenda/)? Then attend our breakfast panel on barriers to leadership as well! #nPOD2024 @LinnemannLab @rmirmira @jessdunnephd @gFousteri @TseHubert @DiabetesnPOD
So excited to see where this important work goes!
Thrilled to represent @IUDeptPeds and co-lead the newly funded Heartland Children’s Nutrition Collaborative with @ssimsek22 from @PurdueFoodSci. We're extremely grateful for the Ricks Family Foundation's investment in pediatric health and precision nutrition research
@rmirmira @SarahTersey @NIDDKgov 🙌🙌🙌 @SarahTersey
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Mark A. Atkinson @matkinsonT1D
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